Wednesday May 25
| 09.15 - 12.30 |
Course: Microdialysis in Neurocritical Care
(see specific program)
Uppsala University Hospital, Uppsala |
| from 13.30 |
Registration |
| 14.00 - 14.15 |
Opening of the conference |
| |
SESSION 1: Translational Microdialysis |
| 14.15 - 14.45 |
Keynote speaker Elizabeth CM de Lange:
Indispensable Role of Microdialysis in Translational CNS Pharmacokinetics-Pharmacodynamics. Leiden Univ, the Netherlands |
| 14.45 - 15.15 |
William Couet:
Comparison Between Microdialysis ECF and CSF Sampling of Drugs in Critical Care Patients. University of Poitiers, France |
| 15.15 - 16.00 |
Coffee and poster-viewing |
| 16.00 - 16.30 |
Tung-hu Tsai: A strategy of in-vivo microdialysis for pre-clinical pharmacokinetic study.
National Yang-Ming University, Taipei, Taiwan |
| 16.30 - 16.45 |
Florian Slimano:
Combining microdialysis and pharmacokinetic modelling. University of Reims, France |
| 16.45- 17.45 |
Posters |
| 18.30- 20.30 |
Welcome Reception at Carolina Rediviva (University Library) |
Thursday May 26
| |
SESSION 2: Microdialysis and Analytical Aspects.
Session Devoted to the Memory of Professor Craig E Lunte |
| 08.30 - 09.00 |
Keynote speaker Julie A Stenken:
In vivo microdialysis sampling in tissue engineering: Expanding applications into pharmaceutical intervention of the foreign body reaction. University of Arkansas, USA |
| 09.00 - 09.30 |
Susan Lunte: Separation based approaches for the analysis of microdialysis samples.
University of Kansas, Lawrence, USA |
| 09.30 - 10.00 |
Andreas Dahlin: Microdialysis sampling of proteins: Fluid characteristics, extraction efficiency and enhanced performance. Uppsala University, Sweden |
| 10.00 - 10.15 |
Janusz Pawliszyn: SPME, a complementary tool for microdialysis for in-vivo investigations: Rat brain and plant sampling. University of Waterloo, Canada |
| 10.15 - 10.45 |
Coffee and poster-viewing |
| |
SESSION 3: Low Molecular Biomarker Matters |
| 10.45 - 11.15 |
Oliver Sakowitz:Spreading depression and cerebral microdialysis - implications for neurointensive care. Academic teaching hospital of the University of Heidelberg, Germany |
| 11.15 - 11.45 |
Bo-Mikael Bellander: title t.b.a., Karolinska Institutet, Stockholm, Sweden |
| 11.45 - 12.00 |
Carl-Henrik Nordström: Ischemia, mitochondrial dysfunction and evaluation of global energy state - Focus on the LP ratio, Odense University Hospital, Denmark |
| 12.00 - 12.15 |
Keri Carpenter: Succinate perfused focally enters the tricarboxylic acid cycle and potentiates cerebral metabolism in traumatic brain injury patients: a 13C-labelled microdialysis and high-resolution NMR study.University of Cambridge, UK |
| 12.15 - 14.00 |
Lunch (change of posters) |
| |
SESSION 4: Pharmacokinetic Aspects Studied with Microdialysis |
| 14.00 - 14.30 |
Hartmut Derendorf: The Street Light Effect - Target Site Concentration Measurements in Drug Development Using Microdialysis. University of Florida, Gainesville, USA |
| 14.30 - 15.00 |
Ken-ichi Hosoya: Microdialysis for evaluating the efflux transport of drugs across the blood-retinal barrier. University of Toyama, Japan |
| 15.00 - 15.15 |
Yin Cheong Wong: Linking pharmacokinetics to CNS dopamine D2-receptor occupancy. Leiden University, the Netherlands |
| 15.15 - 16.00 |
Coffee and poster-viewing |
| 16.00 - 16.15 |
Carles Monterrubio: Local drug delivery in neuroblastoma. Hospital Sant Joan de Déu Barcelona, Spain |
| 16.15 - 16.30 |
Gisli Björn Bergmann: Monitoring liver grafts in pediatric recipients. Oslo University Hospital and Faculty of Medicine, Norway |
| 16.30 - 17.00 |
Information on latest development from companies |
| 17.00 - 18.00 |
Posters |
| 19.00 - 22.00 |
Conference dinner at Clarion Hotel Gillet |
Friday May 27
| |
SESSION 5: Microdialysis Applications |
| 08.30 - 09.00 |
Markus Zeitlinger: Microdialysis in modern drug development, University of Vienna, Austria |
| 09.00 - 09.30 |
Manfred Bodenlenz: The use of membrane-free open-flow microperfusion for studies into the PK-PD of large molecules, Joanneum Research Center, Graz, Austria |
| 09.30 - 09.45 |
Eric Thelin: Microdialysis monitoring of cerebrospinal fluid, subcutaneous tissue and brain tissue reveals temporal patterns and correlations of glucose and lactate. Karolinska Institutet, Stockholm, Sweden. |
| 09.45 - 10.00 |
Thomas Cremers: From rodent to primate: microdialysis in translational research, an invaluable tool. Brains On Line BV, Groningen, The Netherlands |
| 10.00 - 10.15 |
Fredrik Clausen: A comparison between 1 MDa and 100 kDa microdialysis probes on cerebral chemokine and cytokine capture after experimental traumatic brain injury. Uppsala University, Sweden |
| 10.15 - 10.45 |
Coffee and poster-viewing |
| |
SESSION 6: Future Perspectives of Microdialysis |
| 10.45 - 11.15 |
Keynote speaker Peter Hutchinson:
Clinical application of microdialysis in Neuro-intensive Care.
University of Cambridge and Addenbrooke's Hospital, Cambridge, UK |
| 11.15 - 11.45 |
Masood Kamali Moghadam: Advanced Molecular Technologies for Protein Analysis and Diagnostics., Uppsala University, Sweden |
| 11.45 - 12.00 |
Sebastian Schroepf and Daniela Bureau: Microdialysis for therapeutic drug monitoring in infants. Dr. von Hauner Children’s Hospital, Munich, Germany |
| 12.00 - 12.15 |
Jonas Bergquist: Protein adsorption to microdialysis membranes studied by quantiative mass spectrometry. Uppsala University, Sweden |
| 12.15 - 12.30 |
Concluding Remarks and End of Conference |
| 12.30 - 13.00 |
Lunch (sandwich to-go) |
| 14.00 - 17.30 |
Course: Preclinical Quantitative Microdialysis
(see specific program)
Biomedical Centre, Uppsala |
|
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